This talk is a distillation of the recently published book ``Physics from Fisher Information'' by B. Roy Frieden of the University of Arizona (CUP 1998). In this book Frieden presents a fundamentally new approach to the whole of Physics, and proposes a new unifying principle, Extreme Physical Information (EPI) which yields spectacular results. The main aim of the talk is to explain what is meant by ``Fisher Information'', to present the EPI principle, and encourage reading of the book by all active physicists.